The 7th European Lipidomics Meeting will take place from 26-29 September 2018 in Leipzig, Germany.

Members of LIFS and the lipidomics standards initiative will be present at the event, giving various keynote presentations and presenting software tools and standardization guidelines for lipidomics.

The following table gives an overview of the timetable of LIFS and LSI related talks and workshop at the venue.

DayTimeSessionWhatWhoAffiliation
September 26th 16:15 - 18:00 Satellite workshop Satellite workshop organized by Lipidomics Standards
Initiative
Kim Ekroos, Lipidomics Consulting Ltd, Finland
Gerhard Liebisch, University of Regensburg, Regensburg, Germany
Lipidomics Standards Initiative (LSI)
September 27th 9:10 - 9:40 Session 1: Analytical Methods Development for Lipidomics Ultra-high-resolution mass spectrometry  and what it brings  to shotgun lipidomics Andrej Shevchenko, MPI-CBG Dresden, Dresden, Germany Lipidomics Informatics for Life Sciences
September 28th 13:30 – 14:30 Lipidomics Software Demo PeakStrainer and LipidXplorer Eduardo Jacobo Miranda Ackerman, MPI-CBG Dresden, Dresden, Germany Lipidomics Informatics for Life Sciences
September 28th 8:30 - 9:00 Session 3:
Bioinformatics solutions for Lipidomics
LIFS: Lipidomics informatics for life-science Robert Ahrends,
Leibniz Institute for Analytical Sciences – ISAS, Dortmund, Germany
Lipidomics Informatics for Life Sciences
September 28th 15:10 - 15:40 Session 5: Clinical Lipidomics Tissue lipidomics: about the challenge to correlate clinical data and
histological phenotypes with lipid metabolic snapshots
Dominik Schwudke,
Research Center Borstel, Borstel, Germany
Lipidomics Informatics for Life Sciences
September 29th 11:50 - 12:10 Session 6: Integration of Lipidomics into Systems
Medicine Research
Guidelines for lipidomics analysis and reporting – the Lipidomics Standards Initiative (LSI) Gerhard Liebisch, University of Regensburg, Regensburg, Germany Lipidomics Standards Initiative (LSI)

 

The following table gives an overview of the timetable of LIFS related posters at the venue.

DayTimeSessionWhatWhoAbstract
September 27th 17:40 - 19:00 Poster Session (odd numbers) P3.3: Peakstrainer and LipidXplorerWeb for Online Shotgun Lipidomics Processing Pipeline Jacobo Miranda Ackermann, MPI CBG, Dresden, Germany LipidXplorerWeb is an enhanced online version of the free and open-source software kit LipidXplorer. It supports the identification and quantification of molecular species of any lipid class detected by shotgun experiments performed on any mass spectrometry platform. In contrast to the local installation, the internet version provides continuous enhancements and corrections to simplify the lipid identification routines based on users experience and requirement. For example users can select predefined collections of MFQL files (molecular fragmentation query language), or create their own and share them with other. Automated configuration generation, as well as warning for unexpected setting, make it easier for the user to implement the workflow. The major drawback of online processing is the large file sizes that need to be transferred, to mitigate this issue PeakStrainer can be run on a local installation and generate files where noise peaks are filtered out (without loosing low intensity signals) and the data is efficiently packed to minimize upload time, this allows batch processing of multiple shotgun acquisitions by high-resolution mass mapping, precursor and neutral-loss scanning, and data-dependent MS/MS. While the internet version is suitable for a variety of lipidomics applications in cell biology and molecular medicine, the flexible nature of MFQL and potential for collaboration and interaction lends itself to diverse applications of small molecule identification in experiments where molecules are consistently processed on a mass spectrometry platform.

LipidomicsForum Banner 2018

Early bird registration and abstract submission have been extended until September 15th 2018. Applications for student travel grants will still be possible after the deadline.

We are very happy to announce the 4th International Lipidomics Forum in Dortmund (ISAS) between 11th and 13th of November 2018 (lipidomics-forum.isas.de/ lipidomics-forum.fz-borstel.de). This symposium is the 4th meeting of an annual series of conferences on lipid biology and lipidomics. The forum provides a platform for interaction of international acknowledged scientists, students and young researchers. Specifically, we encourage young researchers to participate by poster presentations and short talks allowing them to receive advice from experts in the field. This symposium series will not only cover research highlights but also will offer tutorials on selected medical and methodical topics, which are in the focus of the Special Interest Group Lipid Analytics and Lipidomics of the DGMS. Students will be financially supported by travel grants of the DGMS. We are very excited to present this meeting and looking forward to lively discussions and many interactions.

The registration is open; we warmly welcome you to the ISAS Dortmund and looking forward to your visit and contribution.

The Organizers

Robert Ahrends (ISAS), Nils Hoffmann (ISAS), Dominik Kopczynski (ISAS), Nicolas Gisch (RCB) and Dominik Schwudke (RCB)

LipidomicsForum Banner 2018 regOpen

Early bird registration and abstract submission will close on August 30th 2018. Applications for student travel grants will still be possible after the deadline.

We are very happy to announce the 4th International Lipidomics Forum in Dortmund (ISAS) between 11th and 13th of November 2018 (lipidomics-forum.isas.de/ lipidomics-forum.fz-borstel.de). This symposium is the 4th meeting of an annual series of conferences on lipid biology and lipidomics. The forum provides a platform for interaction of international acknowledged scientists, students and young researchers. Specifically, we encourage young researchers to participate by poster presentations and short talks allowing them to receive advice from experts in the field. This symposium series will not only cover research highlights but also will offer tutorials on selected medical and methodical topics, which are in the focus of the Special Interest Group Lipid Analytics and Lipidomics of the DGMS. Students will be financially supported by travel grants of the DGMS. We are very excited to present this meeting and looking forward to lively discussions and many interactions.

The registration is open; we warmly welcome you to the ISAS Dortmund and looking forward to your visit and contribution.

The Organizers

Robert Ahrends (ISAS), Nils Hoffmann (ISAS), Dominik Kopczynski (ISAS), Nicolas Gisch (RCB) and Dominik Schwudke (RCB)

We are looking for a master student (m/f/v) in Bioinformatics / Informatics for the research group Bioanalytical Chemistry (PD Dr.
Schwudke) at this time in the field of Lipidomics.

The goal of this master's thesis is to develop algorithms that will allow to incorporate lipid quantities into the lipidome homology computation. For this purpose an optimization function needs to be defined that helps to maximize the accuracy of the homology metric and should improve associations of phenotypic data to lipidomes (Eggers et al. Scientific Reports 2017).

The Research Center Borstel is an international science company, funded by the German federal government and the state of Schleswig-Holstein with 550 employees. Our central task is research and patient care in the field of respiratory diseases. We operate both, infrastructure of basic research as well as a medical clinic.

We have one goal: to improve existing methods for the detection, prevention and treatment of lung diseases and to develop new, innovative therapeutic approaches.

The Research Center Borstel encourages female candidates to apply and will be treated favourably in case of equal qualification. Disabled applicants with equal qualifications will be considered on a preferential basis.

For further information, please contact:
PD Dr. Dominik Schwudke, Email: This email address is being protected from spambots. You need JavaScript enabled to view it. or
Dr. Fadi Al Machot Email: This email address is being protected from spambots. You need JavaScript enabled to view it..

Applicants are requested to send their cover letter, CV without picture and list of publication until December 1st, 2018 only via email to: This email address is being protected from spambots. You need JavaScript enabled to view it..

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The 66th ASMS Conference on Mass Spectrometry and Allied Topics of the American Society for Mass Spectrometry took place in San Diego from June 2nd to June 7th.

Before the actual conference, Bing Peng and Robert Ahrends participated in the Skyline User Group meeting
and presented the latest advances in LipidCreator, a Skyline plugin for targeted lipidomics.


Members of LIFS and the associated Lipidomics groups were present at the main conference with a diverse number of posters and presentations:

Posters:

MP 469 Proposal for a common nomenclature for fragment ions in mass spectra of lipids

Josch K Pauling [1]; Martin Hermansson [1]; Peter Husen [1]; Jürgen Hartler [2]; Sandra F. Gallego [1]; Bing Peng [3]; Robert Ahrends [3]; Christer Ejsing* [1] [4]

[1] University of Southern Denmark, Odense, Denmark; [2] Graz University of Technology, Graz, Austria; [3] ISAS, Dortmund, Germany; [4] EMBL, Heidelberg, Heidelberg, Germany

 

TP 466 Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome

Bing Peng [1]; Sascha Geue [2]; Cristina Coman [1]; Dominik Kopczynski [1]; Patrick Münzer [2]; Albert Sickmann [1]; Meinrad Gawaz [2]; Oliver Borst [2]; Robert Ahrends* [1]

[1] ISAS, Dortmund, Germany; [2] Department of Cardiology and Cardiovascular Medicine, Tuebingen, Germany

 

WP 511 Laser capture microdissection coupled with shotgun profiling reveals full-lipidome zonation in liver

Olga Vvedenskaya*; Oskar Knittelfelder; Sofia Traikov; Andrej Shevchenko

Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany

 

WP 520 LipidCreator: A new bridge between targeted and non-targeted LC-MS/MS-based lipidomics

Bing Peng* [1]; Dominik Kopczynski [1]; Nils Hoffmann [1]; Brian Pratt [2]; Dominik Schwudke [3]; Christer S. Ejsing [4] [5]; Brendan MacLean [2]; Robert Ahrends [1]

[1] ISAS, Dortmund, Germany; [2] University of Washington Genome Sciences, Seattle, WA; [3] Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany; [4] University of Southern Denmark, Odense, Denmark; [5] Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany

 

Oral presentations:

Guidelines for Lipidomics Analysis and Reporting – the Lipidomics Standards Initiative (LSI)

Gerhard Liebisch* [1]; John A. Bowden [2]; William J. Griffiths [3]; Robert Ahrends [4]; Todd W Mitchell [5]; Makoto Arita [6]; Christer Ejsing [7]; Michal Holčapek [8]; Markus R. Wenk [9]; Kim Ekroos [10]

[1] Institute of Clinical Chemistry and Laboratory Medicine, University of Regensburg, Regensburg, Germany; [2] Chemical Sciences Division, Hollings Marine Laboratory, National Institute of Standards and Technology, USA, Charleston, SC; [3] Swansea University Medical School, ILS1 Building, Singleton Park, Swansea, United Kingdom; [4] Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany; [5] School of Medicine, Illawarra Health and Medical Research Institute, University of Wollongong, NSW 2522, Wollongong, Australia; [6] Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences (IMS), Tsurumi, Kanagawa 230-0045, Yokohama, Japan; [7] Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230, Odense, Denmark; [8] Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic; [9] Singapore Lipidomics Incubator (SLING), Department of Biochemistry, YLL School of Medicine, National University of Singapore, Singapore, Singapore; [10] Lipidomics Consulting Ltd., FI-02230, Esbo, Finland