Today, we are very pleased to announce the SpeCS v.0.6 release which applies the spectral comparison score (SCS) algorithm score LMs in relation to their structural similarity enabling a well-defined quality control approach for PRM based quantitation. The score is based on the Spearman’s rank correlation between fragment intensities in the query and library as well as the number of matched fragment. To automatize the scoring the software “SpeCS” was developed to

1) process raw peak lists,

2) generate customized spectral libraries,

3) perform SCS calculations, and

4) help to identify quantifier ions.

A set of filters can be employed to delete background signals and/or select only fragments that fit the compositional constraint of CnH3/2n-yOz (n=4,5,6…22; y: 0,1,2; z=0,1,2..5).

Download SpeCS v.0.6.

SpeCS for Windows

 

New in this release


Specs

Publications

Adam Wutkowskia, Matthias Krajewski, Navratan Bagwan, Mathias Schäfer, Bhesh R.Paudyal, Ulrich E. Schaible, Dominik Schwudke,

Software-aided quality control of parallel reaction monitoring based quantitation of lipid mediators,

Analytica Chimica Acta (2018),doi:10.1016/j.aca.2018.01.044

Bioanalytical Chemistry - Research Center Borstel

Dr. Domink Schwudke - Research group leader
Dr. Adam Wutkowski - Research Center Borstel

Lipidomics Forum 2018

The Lipidomics Forum 2018 will take place at the Leibniz Institute for Analytical Sciences - ISAS e.V. - Dortmund, Germany, from November 11th to 13th 2018.

It brings together international specialists and experts in the field and offers a unique opportunity
to present current research and exchange ideas on the upcoming hot topics of lipidomics.

Lipidomics Forum 2018 is joining forces with the LipidMaps consortium to boost lipidomics community efforts and visibility.

The organizers are happy to announce the following keynote speakers:

  • Michal Holčapek -
Department of Analytical Chemistry, Pardubice, Czech Republic
  • Ivan Tancevski -
Department of Internal Medicine, Innsbruck, Austria
  • Valerie O'Donnell -
Systems Immunity Research Institute, Cardiff, UK
  • Thorsten Hornemann -
Medical faculty, Zürich, Switzerland
  • Gerhard Liebisch -
Clinical chemistry, Regensburg, Germany
  • Rainer Lehmann -
Department of Internal Medicine, University Hospital, Tübingen, Germany

 

More information can be found on the venue's homepage.

The Lipidomics Forum 2017 will take place at the Leibniz Institute Research Center Borstel, Germany, from November 12th to 14th.

It brings together international specialists and experts in the field and offers a unique opportunity
to present current research and exchange ideas on the upcoming hot topics of lipidomics.

Registration is still open for last minute attendance.

Please register here.

The LIFS consortium has published its first overview and perspective article on the LIFS project:

Lipidomics informatics for life-science

J Biotechnol. 2017 Aug 16. pii: S0168-1656(17)31596-1. doi: 10.1016/j.jbiotec.2017.08.010.

 

The Lipidomics Forum 2017 will take place at the Leibniz Institute Research Center Borstel, Germany, from November 12th to 14th.

It brings together international specialists and experts in the field and offers a unique opportunity
to present current research and exchange ideas on the upcoming hot topics of lipidomics.

Early registration with reduced registration fees for the Lipidomics Forum 2017 will end on September 30th, 2017.

Please register here.